Any transdermal patch manufacturer is faced with common challenges for assembling transdermal drug delivery system, including:
With a proven approach that has adapted to these and other challenges faced by transdermal patch manufacturers, we have a solution.
Our solution to all these challenges is based on a modular transdermal machine
that uses proven designs to mitigate risk.
Because our cutting and placement methods are so precise, our clients
have achieved material savings in the 10-50% range.
By integrating inspection, printing, packaging and robotics into our modular machines, we can move you from a 2-pass manufacturing approach to a 1-pass approach.
A 1-pass approach from raw material to packaged transdermals will help you:
Precise die cutting and placement technologies: Using our advanced die cutting and placement techniques, you can achieve smaller cuts with less scrap, maximizing your drug utilization. Additional scrap may be reduced by combining our die cutting modules with our inline MOD-TRACK™ Vision System to provide closed loop cutting corrections in real time.
Advanced tension control: Our advanced servo motor control allows precise tension control that can be perfected throughout the process to eliminate product curl.
Lot / date code printing: Seamless integration of OEM lot and date code printers that can be programed from your machines touchscreen interface.
Vision inspection of products: Our MOD-TRACK™ Vision System can be added to confirm product quality and update the registration position to assist in maintaining the best CPK for the process.
Heat-seal pouching: Our patented reciprocating heat seal technology allows for a repeatable seal time, temperature and pressure settings with continuous high speed motion.
Reject, shingling and stacking conveyors: Our conveying modules offer a variety of part handling functions and help ensure quality product verification. Part reject conveyors remove non-conforming parts with variety of lane options. Shingling and stacking conveyors allow for stacked parts with specific counts. Spreading and transfer conveyors are designed for process requirements.
Integration of end-of-line packaging and robotics: Masters in Motion® – Our team excels in the integration with OEM systems allow for complete automated manufacturing systems, controlled from one Touchscreen HMI.
Validation support for IQ/OQ/PQ: Accelerate your time to market! Utilize the experience of our validation team who are adept at working with our proven machine modules and a variety of converting processes. Our validation services are modeled after GAMP and allow the flexibility to work with you and your project needs.
CFR 21 Part 11 Compliance Tools: We are committed to delivering high quality systems that give customers the capability to comply with 21 CFR Part 11 and efficiently complete the validation of their machines.
These machines don’t design themselves. They also require the right training and support to ensure you’re running them at maximum efficiency. That’s why offer:
Application process and machine support
Keeping your machines running is priority #1. Most support can be done over the phone with an internet connection to the machine.
“Proof of principle” service for new products and processes
We can verify that the process / product can be produced within the customer specification.
Validation and documentation support
We can provide IQ/OQ/PQ support and custom documentation deliverables
You’ve read a lot about us, so now can we hear about you?
In the manufacture of any medical device or pharmaceutical product, validation and verification are two pivotal terms. We’ll break down the differences and use the production of a transdermal patch to provide examples of how they apply to the manufacturing process.Read more
We’ve seen plenty of industry disruptors with the likes of Amazon and Uber. In the case of transdermal microneedle patches, the impact extends beyond typical business metrics like price or customer convenience. This is an innovation that can help us deal with an escalating global health crisis.Read more
Entering into the transdermal medication market is no easy task. It’s a market segment heavy in regulations, tight on tolerances, and requires precision equipment. While the profit margins can be substantial, it will require a major investment in resources and talent.Read more